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| Status |
Public on May 23, 2018 |
| Title |
DNA methylation-mediated regulation of adipose tissue macrophages during high-fat diet-induced obesity |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
We used MeDIP-Seq to screen for genes that may be regulated by DNA methylation in macrophages isolated from adipose tissue of lean and obese mice.
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| Overall design |
F4/80+ adipose tissue macrophages were isolated from epididymal fat of mice fed a 10% low fat diet, (LFD, lean mice) or 60% high-fat diet (HFD, obese mice) for 16 weeks.
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| Contributor(s) |
Miranda K, Yang X, Bam M, Nagarkatti P, Nagarkatti M |
| Citation(s) |
29899524 |
| |
| Submission date |
May 22, 2018 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Prakash Nagarkatti |
| E-mail(s) |
prakash@mailbox.sc.edu
|
| Organization name |
University of South Carolina School of Medicine
|
| Street address |
6439 Garners Ferry Road
|
| City |
Columbia |
| State/province |
SC |
| ZIP/Postal code |
29209 |
| Country |
USA |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA472629 |
| SRA |
SRP148765 |
