GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE114169 Query DataSets for GSE114169
Status Public on Sep 12, 2018
Title Effect of an Analgesic Drug on Necelus Pulposus Cells from Human Intervertebral Disc (IVD) Tissues
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Neurotropin (NTP), a non-protein extract from inflamed rabbit skin inoculated with vaccinia virus. It has been widely used in Japan to treat low back pain. The current sutudy evaluated its stimulative effect on the disc cells to enhance glycosaminoglycan synthesis, which is one of the most important functions of the cells.
Gene expression profile was exzamined in the cells treated with or without NTP in vitro.
Overall design Cultured human nucleus pulposus cells were treated with NTP every second day for a week. Total RNA was prepared from the harvested cells, and analyzed gene expression. RNA from the cells cultured in the basal medium for the same time period was used as control.
Contributor(s) Sakai D, Nakai T
Citation(s) 30148873
Submission date May 08, 2018
Last update date Sep 12, 2018
Contact name Tomoko Nakai
Phone +81-463-93-1121
Organization name Tokai University School of Medicine
Department Orthopaedic Surgery, Surgical Science
Street address Shimokasuya143
City Isehara
State/province Kanagawa
ZIP/Postal code 259-1193
Country Japan
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (8)
GSM3136798 Donor1_control
GSM3136799 Donor1_treatment
GSM3136800 Donor2_control
BioProject PRJNA467767

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE114169_RAW.tar 24.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap