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Series GSE113073 Query DataSets for GSE113073
Status Public on May 13, 2018
Title Transcription Factor SOX30 Is a Key Regulator of Mouse Spermiogenesis
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary As Sox30 knockout arrests spermatogenesis at the step 3 round spermatid (rST) stage, we performed RNA sequencing to identify genes regulated by Sox30.
 
Overall design We conducted RNA-sequencing (RNA-seq) analysis to identify SOX30-regulated genes that were differentially expressed in rST of Sox30 KO and WT mice. rST were isolated by FACS from 23 dpp (days postpartum) WT and KO mice, a stage where spermatogenesis progress to step 3 rST with no extra haploid cell types present.
 
Contributor(s) Zhang D, Lin X, Han C
Citation(s) 29848638
Submission date Apr 12, 2018
Last update date Mar 01, 2019
Contact name Chunsheng Han
E-mail(s) hancs@ioz.ac.cn
Phone 86-10-64807105
Organization name Chinese Academy of Sciences
Department Institute of Zoology
Lab State Key Laboratory of Reproductive Biology
Street address 1-5 Beichen West Road, Chaoyang District
City Beijing
State/province Beijing
ZIP/Postal code 100101
Country China
 
Platforms (1)
GPL21273 HiSeq X Ten (Mus musculus)
Samples (4)
GSM3095776 Round spermatid sample from 23 dpp wildtype mice-1
GSM3095777 Round spermatid sample from 23 dpp Sox30 knockout mice-1
GSM3095778 Round spermatid sample from 23 dpp wildtype mice-2
Relations
BioProject PRJNA449928
SRA SRP139811

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE113073_RAW.tar 630.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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