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Series GSE112558 Query DataSets for GSE112558
Status Public on Oct 18, 2018
Title RNA-sequencing to investigate transcriptional changes caused by ZNF384 fusion proteins in murine pre-B cells
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary RNA-sequencing was performed on Arf-/- pre-B cell expressing either wild-type ZNF384, TAF15-ZNF384, or TCF3-ZNF384. We found that pre-B cells that express ZNF384 fusion proteins have a gene expression profile similar to patients with ZNF384-rearranged leukemia.
Overall design 2 biological replicates of 3 genetically-modified cells lines
Contributor(s) Mullighan CG, Dickerson KM, Xu B
Citation(s) 30209392
Submission date Mar 30, 2018
Last update date Mar 08, 2019
Contact name Beisi Xu
Organization name St Jude Children's Research Hosipital
Department Center for Applied Bioinformatics
Street address 262 Danny Thomas Pl
City Memphis
State/province Tennessee
ZIP/Postal code 38105
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (8)
GSM3073005 RNA_C30-ZNF384WT-CHA replicate 2
GSM3073006 RNA_C31-ZNF384WT-CHA replicate 1
GSM3073007 RNA_C21-EV replicate 1
This SubSeries is part of SuperSeries:
GSE112561 Genomic classification and identification of the cell of origin of pediatric mixed phenotype acute leukemia
BioProject PRJNA448177
SRA SRP136838

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE112558_RNASeq_counts.mm9.txt.gz 324.4 Kb (ftp)(http) TXT
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