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Series GSE11247 Query DataSets for GSE11247
Status Public on Apr 01, 2010
Title Peripheral blood stem cell gene profiling
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Mobilized-peripheral blood hematopoietic stem cells (HSCs) have been used for transplantation, immunotherapy, and cardiovascular regenerative medicine. Agents used for HPC mobilization include G-CSF and the CXCR4 inhibitor AMD3100. The HSCs cells mobilized by each agent may contain different subtypes and have different functions. To characterize mobilized HSCs used for clinical applications, microRNA (miRNA) profiling and gene expression profiling were used to compare AMD3100-mobilized CD133+ cells from 4 subjects, AMD3100 plus G-CSF-mobilized CD133+ cells from 4 subjects and G-CSF-mobilized CD34+ cells from 5 subjects. The HSCs were compared to peripheral blood leukocytes (PBLs) from 7 subjects.
Keywords: cell type comparison design
 
Overall design gene expression profiling were used to compare AMD3100-mobilized CD133+ cells from 4 subjects, AMD3100 plus G-CSF-mobilized CD133+ cells from 4 subjects and G-CSF-mobilized CD34+ cells from 5 subjects. The HSCs were compared to peripheral blood leukocytes (PBLs) from 7 subjects.
 
Citation(s) 18647411
Submission date Apr 23, 2008
Last update date May 25, 2012
Contact name Francesco Maria Marincola
E-mail(s) fmarincola@sidra.org
Phone 301-793-8210
Organization name Sidra Medical and Research Center
Street address Al Nasr Tower, AL Corniche Street, PO Box 26999
City Doha
ZIP/Postal code PO Box 26999
Country Qatar
 
Platforms (1)
GPL5959 CCDTM Hs_CCDTM17.5k version 2
Samples (41)
GSM283952 Donor 4 - CD34 - GCSF - mAdbID:81746
GSM283953 Donor 2 - CD34 - GCSF - mAdbID:81748
GSM283954 Donor 1 - CD34 - GCSF - mAdbID:81753
This SubSeries is part of SuperSeries:
GSE11255 Peripheral blood stem cell gene and microRNA profiling
Relations
BioProject PRJNA109189

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE11247_RAW.tar 73.6 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table
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