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Series GSE112459 Query DataSets for GSE112459
Status Public on Dec 29, 2019
Title Expression data of miRNAs from splenic leukocytes of dogs infected with L. infantum
Platform organism synthetic construct
Sample organism Canis lupus familiaris
Experiment type Non-coding RNA profiling by array
Summary The disease visceral leishmaniasis (VL), caused by Leishmania (L.) infantum, its a serious public health problem in Brazil. Studies with miRNAs showed their regulation in the immune response, due to cell immune suppression to be determinant at disease progression, identify them is important for the mechanism of change in immune response. We suggest then, that miRNAs regulation at immune response of dogs with VL.
Overall design Fourteen dogs were used to form two groups for the study: 5 healthy dogs in Control group and 9 dogs naturally infected with L. infantum in Infected group.
Contributor(s) Melo LM, Bragato JP, Venturin GL, Rebech GT, de Araújo Júnior EC, Garcia LE, Eugênio FR, dos Santos PS, Lopes FL, Lima VM
Citation(s) 31825987
Submission date Mar 28, 2018
Last update date Dec 29, 2019
Contact name Larissa Martins Melo
Organization name UNESP
Street address Clovis Pestana st, 793
City Araçatuba
ZIP/Postal code 16050-680
Country Brazil
Platforms (1)
GPL19117 [miRNA-4] Affymetrix Multispecies miRNA-4 Array
Samples (14)
GSM3070419 LE of infected dogs_rep1
GSM3070420 LE of infected dogs_rep2
GSM3070421 LE of infected dogs_rep3
BioProject PRJNA447431

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Supplementary file Size Download File type/resource
GSE112459_RAW.tar 11.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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