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Series GSE112300 Query DataSets for GSE112300
Status Public on Mar 01, 2019
Title Identification of HOXB13 target genes responsive to BET inhibitors
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We identified BRD4 as an epigenetic regulator of the prostate lineage specific gene HOXB13 during progression of the disease from an androgen
dependent to an androgen independent state.
 
Overall design Integrative analysis- we compared genes whose expression was significantly impacted either (up or downregulated) as a result of HOXB13 knockdown and were also sensitive to BET inhibition
 
Contributor(s) Mahajan K, Perera R
Citation(s) 30242092
Submission date Mar 24, 2018
Last update date Mar 01, 2019
Contact name Kiran Mahajan
E-mail(s) kiranm@wustl.edu
Phone 3142737728
Organization name Washington University
Department Surgery
Lab Kiran Mahajan Lab
Street address CB 8242 600 South Euclid Ave
City St. Louis
State/province Missouri
ZIP/Postal code 63110
Country USA
 
Platforms (1)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
Samples (9)
GSM3067344 C4-2B DMSO (rep1)
GSM3067345 C4-2B DMSO (rep2)
GSM3067346 C4-2B HOXB13 KO1
Relations
BioProject PRJNA445557
SRA SRP136392

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE112300_RAW.tar 6.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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