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| Status |
Public on Mar 20, 2018 |
| Title |
Gene expression in Fuchs endothelial corneal dystrophy and healthy cultured cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Fuchs endothelial corneal dystrophy (FECD) is a vision impairing pathology affecting the endothelial cells of the cornea. To better understand the disease, we developed a method to cultivate FECD cells isolated from surgical specimens. Using gene profiling, we compared the mRNA profiles of passage 2 FECD cells with passage 2 non-pathological corneal endothelial cells isolated from eye bank donor corneas.
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| Overall design |
Six Fuchs endothelial corneal dystrophy and six healthy eye bank corneal endothelial cells at passage 2 are analyzed by gene profiling
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| |
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| Contributor(s) |
Proulx S, Brunette I, Rochette PJ, Thériault M, Gendron SP, Roy O |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Mar 19, 2018 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Stéphanie Proulx |
| Organization name |
Université Laval
|
| Street address |
1050 Chemin Ste-Foy
|
| City |
Québec |
| State/province |
Qc |
| ZIP/Postal code |
G1S4L8 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
|
| Samples (12)
|
| GSM3053714 |
EyeBank_cultured_corneal_endothelial_cells_001_rep1 |
| GSM3053715 |
EyeBank_cultured_corneal_endothelial_cells_002_rep1 |
| GSM3053716 |
EyeBank_cultured_corneal_endothelial_cells_003_rep1 |
| GSM3053717 |
EyeBank_cultured_corneal_endothelial_cells_004_rep1 |
| GSM3053718 |
EyeBank_cultured_corneal_endothelial_cells_005_rep1 |
| GSM3053719 |
EyeBank_cultured_corneal_endothelial_cells_006_rep1 |
| GSM3053720 |
FECD_cultured_corneal_endothelial_cells_001_rep1 |
| GSM3053721 |
FECD_cultured_corneal_endothelial_cells_002_rep1 |
| GSM3053722 |
FECD_cultured_corneal_endothelial_cells_003_rep1 |
| GSM3053723 |
FECD_cultured_corneal_endothelial_cells_004_rep1 |
| GSM3053724 |
FECD_cultured_corneal_endothelial_cells_005_rep1 |
| GSM3053725 |
FECD_cultured_corneal_endothelial_cells_006_rep1 |
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| Relations |
| BioProject |
PRJNA439004 |
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