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Series GSE111597 Query DataSets for GSE111597
Status Public on Mar 14, 2018
Title Gene-expression analysis of human embryonic stem cell (HESC-)- derived rosette-forming neural progenitor cells (NPCs) in the presence of lysophosphatidic acid (LPA)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary As part of our study on the effect of LPA on HESC-derived NPCs, we have employed whole genome microarray analysis to identify genes which were up- and downregulated in the presence of LPA compared to non-LPA-treated control-NPCs and which might be involved in the expansion of the apical domain of NPCs and large rosette formation that we observe after LPA-treatment.
 
Overall design Gene-expression of NPCs at rosette passaging number 2 (RP2) that were cultured in plastic 24-well plates and exposed for 2 h, 10 h and 24 h to 0.5 ml N2B27 + FGF2/EGF medium which was initially supplemented with 15 ┬ÁM was performed. Experiments were performed in triplicates.
 
Contributor(s) Medelnik J
Citation(s) 29779899
Submission date Mar 08, 2018
Last update date Jun 21, 2018
Contact name Jan-Philip Medelnik
E-mail(s) jan.medelnik@imp.ac.at
Organization name Research Institute of Molecular Pathology (IMP)
Lab Tanaka
Street address Campus-Vienna-Biocenter 1
City Vienna
State/province Vienna
ZIP/Postal code 1030
Country Austria
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (18)
GSM3034738 control_[noLPA]_replicate1 (2h time point)
GSM3034739 LPA_[25uM]_replicate1 (2h time point)
GSM3034740 control_[noLPA]_replicate2 (2h time point)
Relations
BioProject PRJNA437487

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE111597_RAW.tar 54.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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