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Series GSE110180 Query DataSets for GSE110180
Status Public on Feb 06, 2018
Title Transcriptomic analysis of multiple myeloma cell lines
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We found that a small molecule inhibitor of PRMT4 inhibited cell growth of a subset of multiple myeloma cell lines. To identify biomarkers that predict the sensitivity of myeloma cells to PRMT4 inhibition, we performed transcriptomic analysis of multiple myeloma cell lines.
Overall design Amplicon sequencing of thirteen multiple myeloma cell lines was performed on the Ion Torrent platform. Steady-state gene expression profile of sensitive cells were compaired with that of insensitive cells.
Contributor(s) Nakayama K, Kiba A, Baba Y, Kikuchi K, Tozaki H
Citation(s) 29719619
Submission date Feb 05, 2018
Last update date Mar 01, 2019
Contact name Kazuhide Nakayama
Organization name Takeda Pharmaceutical Company Limited
Department Regenerative medicine Unit
Lab T-CiRA, Kaneko PJ
Street address 26-1
City Muraoka-Higashi 2-chome Fujisawa
State/province Kanagawa
ZIP/Postal code 251-8555
Country Japan
Platforms (1)
GPL17303 Ion Torrent Proton (Homo sapiens)
Samples (13)
GSM2981811 NCI-H929
GSM2981812 RPMI8226
GSM2981813 U266B1
BioProject PRJNA433025
SRA SRP132239

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE110180_RAW.tar 1.2 Mb (http)(custom) TAR (of TXT)
GSE110180_RPM_matrix.txt.gz 577.1 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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