NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE110037 Query DataSets for GSE110037
Status Public on Dec 05, 2019
Title Single cell RNA sequencing time-course of mesenchymal progenitors during regeneration after notexin induced muscle injury
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary After tissue injury mesenchymal progenitors undergo a transient proliferative expansion, morphological transition and migration from their perivascular niche. To gain transcriptomic insights into the MP function in regeneration, a muscle-injury model was employed to activate MPs and follow their contribution to tissue regeneration. To compliment the population RNA seq profile previously obtained and to uncover the suspected heterogeneity of MPs in this context, tdTomato positive cells from selected timepoints were profiled by single cell RNA sequencing.
 
Overall design Single cell RNA-seq analyes of enriched mesenchymal progenitors at selected timepoints during skeletal muscle regeneration.
 
Contributor(s) Scott RW, Underhill TM
Citation(s) 31809738
Submission date Feb 01, 2018
Last update date Feb 19, 2020
Contact name Tully Michael Underhill
E-mail(s) tunderhi@brc.ubc.ca
Phone 604-822-5833
Organization name University of British Columbia
Department Biomedical Research Centre
Street address 2222 Health Sciences Mall
City Vancouver
State/province British Columbia
ZIP/Postal code V6T 1Z3
Country Canada
 
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (5)
GSM2976778 Single cell RNA-seq tdTomato MPs quiescent
GSM2976779 Single cell RNA-seq tdTomato MPs 1 day post notexin injury
GSM2976780 Single cell RNA-seq tdTomato MPs 2 day post notexin injury
This SubSeries is part of SuperSeries:
GSE110038 Hic1 defines quiescent mesenchymal progenitor subpopulations with distinct functions and fates in skeletal muscle regeneration
Relations
BioProject PRJNA432604

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE110037_RAW.tar 118.8 Mb (http)(custom) TAR (of MTX, TSV)
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap