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| Status |
Public on Jan 25, 2018 |
| Title |
ChIP-seq analysis of histone H3K4me3, H3K27Ac and RNA polymerase II (RNApol II) in HuH-7 cells. |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
The RNA-seq profile of the novel LIN28B variant suggested an alternative transcription initiation (ATI) site approximately 20 kb upstream of LIN28B-WT. Chromatin immunoprecipitation sequencing (ChIP-seq) revealed significant enrichment of histone H3K4me3, H3K27Ac and RNA polymerase II (RNApol II) near the ATI site.
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| |
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| Overall design |
Examination of histone H3K4me3, H3K27Ac and RNA polymerase II (RNApol II) in HuH-7 cells.
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| Contributor(s) |
Huang S, Guo W |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 24, 2018 |
| Last update date |
Dec 23, 2018 |
| Contact name |
Shenglin Huang |
| Organization name |
Fudan University
|
| Street address |
270 Dongan
|
| City |
Shanghai |
| ZIP/Postal code |
200032 |
| Country |
China |
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| Platforms (1) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA431417 |
| SRA |
SRP131262 |
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