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| Status |
Public on Jul 16, 2008 |
| Title |
Immune Dysregulation/Tumor-Associated Gene Changes in Recurrent Respiratory Papillomatosis: A Paired Microarray Analysis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The goal of this study was to determine the differential expression of specific genes within the papilloma tissues themselves and to characterize the array of host genes that might be important in the pathophysiology of recurrent respiratory papillomatosis.
Keywords: papilloma vs normal adjacent autologous larynx
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| Overall design |
Total RNAs from papillomas (n=12) and adjacent tissues (n=12) were analyzed by Affymetrix microarray, and the matched sets of tissues compared by Genesifter paired t-test to identify differentially expressed genes in papilloma tissues while minimizing variations that are intrinsic to individual patients.
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| |
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| Contributor(s) |
Devoti JA, Rosenthal DW, Wu R, Abramson AL, Steinberg BM, Bonargua VR |
| Citation(s) |
18607510 |
| |
| Submission date |
Mar 25, 2008 |
| Last update date |
Dec 06, 2018 |
| Contact name |
James Allen DeVoti |
| E-mail(s) |
jdevoti@lij.edu
|
| Phone |
516-562-1107
|
| URL |
http://www.northshorelij.com/body.cfm?ID=9500
|
| Organization name |
Feinstein Institute for Medical Research
|
| Department |
Immunology and Inflammation
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| Lab |
Bonagura Lab
|
| Street address |
350 Community Drive, Rm 140
|
| City |
Manhasset |
| State/province |
NY |
| ZIP/Postal code |
11030 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA107247 |
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