|
| Status |
Public on Feb 04, 2020 |
| Title |
Hypoxia-induced priming of microglial inflammatory gene expression is associated with TLR4 signaling H3K4me3 enrichment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We analyzed genome-wide H3K4me3 enichment and performed RNAseq analyses in N9 microglia cells after hypoxia exposure
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| |
|
| Overall design |
Examination of H3K4me3 in five experiments in which cells were exposed to either normoxia (21% O2) or hypoxia (1% O2); examination of total mRNA from three experiments in which cells were exposed to normoxia or hypoxia
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| |
|
| Contributor(s) |
Watters JJ, Kiernan EA |
| Citation |
https://www.biorxiv.org/content/10.1101/2020.02.03.933028v1
|
| Submission date |
Jan 04, 2018 |
| Last update date |
Feb 04, 2020 |
| Contact name |
Jyoti Watters |
| E-mail(s) |
jjwatters@wisc.edu
|
| Phone |
6082656092
|
| Organization name |
University of Wisconsin-Madison
|
| Department |
CBS
|
| Lab |
Jyoti Watters
|
| Street address |
2015 Linden Drive
|
| City |
Madison |
| State/province |
WI |
| ZIP/Postal code |
53706 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (28)
|
|
| Relations |
| BioProject |
PRJNA428767 |
| SRA |
SRP130943 |
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