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Series GSE108180 Query DataSets for GSE108180
Status Public on Feb 12, 2018
Title Downregulation of eca-mir-128 in seminal exosomes and enhanced expression of CXCL16 in the stallion reproductive tract are associated with equine arteritis virus long-term persistent infection
Organism Equus caballus
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary We have characterized miRNAs associated with equine seminal exosomes, and identified seminal exosomes eca-mir-128 to be specifically downregulated during equine arteritis virus long-term persistent infection in the reproductive tract of the stallion
 
Overall design We have perfomed small RNAseq on 8 equine seminal exosome samples, including samples from naïve stallions (n=3), and experimentally infected with equine arteritis virus at two different time points (86 days [n=3] and 726 [n=2] days post infection). Findings were further confirmed by RT-qPCR and other experiments were performed to characterize the associateion between eca-mir-128 and the chemokine CXCL16.
 
Contributor(s) Carossino M, Dini P, Kalbfleisch TS, Loynachan AT, Canisso IF, Shuck KM, Timoney PJ, Cook RF, Bailey E, Balasuriya UB
Citation(s) 29444949
Submission date Dec 18, 2017
Last update date Jul 29, 2019
Contact name Theodore Samuel Kalbfleisch
E-mail(s) ted.kalbfleisch@louisville.edu
Phone 502-852-7495
Organization name University of Louisville
Department Biochemistry and Molecular Genetics
Lab Kalbfleisch
Street address 221F Baxter II, 580 S Preston St
City Louisville
State/province KY
ZIP/Postal code 40202
Country USA
 
Platforms (1)
GPL21401 Illumina NextSeq 500 (Equus caballus)
Samples (8)
GSM2891902 L136-pre
GSM2891903 L139-pre
GSM2891904 L140-pre
Relations
BioProject PRJNA422762
SRA SRP126930

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE108180_RAW.tar 280.0 Kb (http)(custom) TAR (of CSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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