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Series GSE107199 Query DataSets for GSE107199
Status Public on May 15, 2018
Title Next Generation Sequencing for Quantitative Transcriptomic Profiling of TLR3, TLR7 and TLR8 Activation in Neurons
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The goal of this study is to compare gene expression of mouse cultured cortical and hippocampal neurons in response to TLR3, TLR7 and TLR8 activation
Overall design At 4 day in vitro, wild-type mouse cortical and hippocampal neurons were treated with vehicle control, poly IC (for TLR3 activation) and CL075 (for TLR7 activation). Tlr7-/- neurons were treated with vehicle control and CL075/poly dT (for TLR8 activation). Six hr after treatment, total RNAs were extracted for deep sequencing, in triplicate, using the NextSeq500 High-output v2 (75 cycle) sequencing kit on the Illumina NextSeq500 instrument.
Contributor(s) Hung Y, Chen C, Hsueh Y
Citation(s) 29777026, 29885943
Submission date Nov 21, 2017
Last update date May 15, 2019
Contact name Yi-Ping Hsueh
Phone 886-2-27899311
Organization name Academia Sinica
Department Institute of Molecular Biology
Lab N514
Street address 128 Academia Road, Section 2, Nankang
City Taipei
ZIP/Postal code 11529
Country Taiwan
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (15)
GSM2862503 WT ctrl rep1
GSM2862504 WT ctrl rep2
GSM2862505 WT ctrl rep3
BioProject PRJNA419291
SRA SRP125379

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE107199_CL075_dT_vs._KO_ctrl_all.xlsx.gz 5.3 Mb (ftp)(http) XLSX
GSE107199_CL075_vs._WT_ctrl_all.xlsx.gz 5.3 Mb (ftp)(http) XLSX
GSE107199_RAW.tar 9.1 Mb (http)(custom) TAR (of TXT)
GSE107199_polyIC_vs._WT_ctrl_all.xlsx.gz 5.4 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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