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GEO accession:
Series GSE107162
Query DataSets for GSE107162
Status
Public on Nov 21, 2017
Title
Application of the transcriptomic biomarker, TGx-DDI, in genotoxicity screening
Organism
Homo sapiens
Experiment type
Expression profiling by array
Summary
Cell-based application of a transcriptomic biomarker, TGx-DDI, in addressing potentially irrelevant positive findings in chromosome damage assays
Overall design
This experiment examined the whole genome transcriptional response of TK6 cells exposed to 45 compounds of the responsive concentration for 4 hours.
Contributor(s)
Li H
,
Chen R
,
Fornace AJ Jr
Citation(s)
29203651
Submission date
Nov 20, 2017
Last update date
Nov 27, 2018
Contact name
Henghong Li
E-mail(s)
hl234@georgetown.edu
Organization name
Georgetown University
Department
Biochemistry
Lab
Fornace
Street address
3970 Reservoir Rd., NW
City
Washington
State/province
DC
ZIP/Postal code
20057
Country
USA
Platforms (1)
GPL13607
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (90)
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More...
GSM2861803
5AzaC 10 uM negative
GSM2861804
5AzaC 10 uM positive
GSM2861805
5FU 400 uM negative
GSM2861806
5FU 400 uM positive
GSM2861807
6-TG 4 uM negative
GSM2861808
6-TG 4 uM positive
GSM2861809
6MP 1 mM negative
GSM2861810
6MP 1 mM positive
GSM2861811
24DNP 1 mM negative
GSM2861812
24DNP 1 mM positive
GSM2861813
Ampicillin 1 mM negative
GSM2861814
Ampicillin 1 mM positive
GSM2861815
AZT 1 mM negative
GSM2861816
AZT 1 mM positive
GSM2861817
Benomyl 1 mM negative
GSM2861818
Benomyl 1 mM positive
GSM2861819
Bleomycin 10 uM negative
GSM2861820
Bleomycin 10 uM positive
GSM2861821
Busulfan 20 uM negative
GSM2861822
Busulfan 20 uM positive
GSM2861823
Chlorambucil 4 uM negative
GSM2861824
Chlorambucil 4 uM positive
GSM2861825
Ciprofloxacin 100 uM negative
GSM2861826
Ciprofloxacin 100 uM positive
GSM2861827
Cycloheximide negative
GSM2861828
Cycloheximide positive
GSM2861829
D-Mannitol 1 mM negative
GSM2861830
D-Mannitol 1 mM positive
GSM2861831
Dasatinib 20 uM negative
GSM2861832
Dasatinib 20 uM positive
GSM2861833
Dexamethasone 1 mM negative
GSM2861834
Dexamethasone 1 mM positive
GSM2861835
Diethanolamine 1 mM negative
GSM2861836
Diethanolamine 1 mM positive
GSM2861837
Diethylstilbestrol 40 uM negative
GSM2861838
Diethylstilbestrol 40 uM positive
GSM2861839
Donepezil 1 mM negative
GSM2861840
Donepezil 1 mM positive
GSM2861841
Doxorubicin 1.2 uM negative
GSM2861842
Doxorubicin 1.2 uM positive
GSM2861843
EMS 2 mM negative
GSM2861844
EMS 2 mM positive
GSM2861845
ENU 500 uM negative
GSM2861846
ENU 500 uM positive
GSM2861847
Erythromycin 500 uM negative
GSM2861848
Erythromycin 500 uM positive
GSM2861849
Esomeprazole 200 uM negative
GSM2861850
Esomeprazole 200 uM positive
GSM2861851
Exemastan 100 uM negative
GSM2861852
Exemastan 100 uM positive
GSM2861853
Gefitinib 100 uM negative
GSM2861854
Gefitinib 100 uM positive
GSM2861855
Genistein 20 uM negative
GSM2861856
Genistein 20 uM positive
GSM2861857
Hydroquinone 20 uM negative
GSM2861858
Hydroquinone 20 uM positive
GSM2861859
Imatinib 400 uM negative
GSM2861860
Imatinib 400 uM positive
GSM2861861
Melamine 1 mM negative
GSM2861862
Melamine 1 mM positive
GSM2861863
Methyl Carbamate 1 mM negative
GSM2861864
Methyl Carbamate 1 mM positive
GSM2861865
MMC 10 uM negative
GSM2861866
MMC 10 uM positive
GSM2861867
N butyl chloride 1 mM negative
GSM2861868
N butyl chloride 1 mM positive
GSM2861869
Nitrogen Mustard 200 nM negative
GSM2861870
Nitrogen Mustard 200 nM positive
GSM2861871
Nocodazole 30 uM negative
GSM2861872
Nocodazole 30 uM positive
GSM2861873
Norfloxacin 1 mM negative
GSM2861874
Norfloxacin 1 mM positive
GSM2861875
Olmesartan 0.16 uM negative
GSM2861876
Olmesartan 0.16 uM positive
GSM2861877
Phenobarbital 1 mM negative
GSM2861878
Phenobarbital 1 mM positive
GSM2861879
Progesterone 1 mM negative
GSM2861880
Progesterone 1 mM positive
GSM2861881
Rabeprazole 0.8 uM negative
GSM2861882
Rabeprazole 0.8 uM positive
GSM2861883
Rotigotin 100 uM negative
GSM2861884
Rotigotin 100 uM positive
GSM2861885
Sorafenib 20 uM negative
GSM2861886
Sorafenib 20 uM positive
GSM2861887
Staurosporine 30 nM negative
GSM2861888
Staurosporine 30 nM positive
GSM2861889
Sunitinb 20 uM negative
GSM2861890
Sunitinib 20 uM positive
GSM2861891
Topotecan 400 nM negative
GSM2861892
Topotecan 400 nM positive
Relations
BioProject
PRJNA419190
Download family
Format
SOFT formatted family file(s)
SOFT
MINiML formatted family file(s)
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Series Matrix File(s)
TXT
Supplementary file
Size
Download
File type/resource
GSE107162_RAW.tar
550.1 Mb
(http)
(custom)
TAR (of TXT)
Processed data included within Sample table
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