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Series GSE106832 Query DataSets for GSE106832
Status Public on Jul 26, 2019
Title Expression profile of lncRNAs and mRNAs in 4 brain regions of adult mouse
Organism Mus musculus
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary We aimed to decipher the spatial expression landscape of well-annotated lncRNAs in brain regions. To this end, we dissected adult male mice brain tissues from olfactory bulb (OB), hypothalamus (Hypo), hippocampus (Hippo) and cerebellum (Cereb) and subjected to Arraystar Mouse LncRNA Microarray V3.0. We found a new type of genome organization formed by highly conserved lncRNA cluster and nearby TF in the non-imprinting regions that is associated with human CNS disorders.
 
Overall design 10-week-old male BALB/c mice (Vital River Laboratories, Beijing, China) were used in this study and the mice were housed in a temperature-controlled room under a 12 hours light/12 hours dark cycle, with free access to food and water ad libitum. Three mice were used for microarray analysis, and three to ten mice were used for validation. The mice were euthanized by cervical dislocation and brains were carefully dissected using stereomicroscope to separate the four experimental brain regions (olfactory bulb, hypothalamus, hippocampus as well as cerebellum) according to mouse brain atlas (26).
 
Contributor(s) Wang F, Ren D, Liang X, Ke S, Zhang B, Hu B, Song X, Wang X
Citation(s) 31127312
Submission date Nov 13, 2017
Last update date Jul 26, 2019
Contact name xiaoyuan song
E-mail(s) songxy5@ustc.edu.cn
Phone 86-551-63607752
Organization name University of Science & Technology of China
Street address Huangshan Road
City Hefei
ZIP/Postal code 230027
Country China
 
Platforms (1)
GPL19286 Arraystar Mouse LncRNA microarray V3B (Agilent-055750 custom Probe Name version)
Samples (12)
GSM2855030 1-1-1
GSM2855031 1-1-4
GSM2855032 1-1-5
Relations
BioProject PRJNA418153

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE106832_RAW.tar 34.6 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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