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Series GSE106130 Query DataSets for GSE106130
Status Public on Mar 03, 2020
Title Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Aim: Identify molecular pathways controlling palate closure
Methods: First pharygneal arch of wild-type and Grhl2-/- e10.5 moues embryos was subjected to RNAseq
Results: Grhl2-/- PA1 displayed a shift from epithelial to mesenchymal gene expression
Conclusions: Grhl2 maintains epithelial cellular identity during palate closure
Overall design First pharygneal arch mRNA profiles of e10.5 mouse embryos wre generated by deep sequencing, with 5 wild-type and 5 knock-out samples, using Illumina HiSeq technology
Contributor(s) Carpinelli M, Wong N
Citation(s) 32005677
Submission date Oct 24, 2017
Last update date Mar 04, 2020
Contact name Nicholas C Wong
Organization name Monash University
Department Monash Bioinformatics Platform, Central Clinical School
Street address Wellington Road
City Clayton
State/province Victoria
ZIP/Postal code 3800
Country Australia
Platforms (1)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (10)
GSM2830191 KO1-588
GSM2830192 KO1-628
GSM2830193 KO2-566
BioProject PRJNA415667
SRA SRP121364

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE106130_featureReverse-proteinCodingFeatures.csv.gz 509.4 Kb (ftp)(http) CSV
GSE106130_processedData.csv.gz 870.9 Kb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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