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Status |
Public on May 19, 2009 |
Title |
Differential gene expression from azithromycin and SMM treated human airway epithelium |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Microarrays were used to evaluate the effects of azithromycin and an inflammatory stimulus (SMM) on human airway epithelium. Effects of azithromycin treatment were evaluated at 6, 24 and 48 hours. Effects of SMM were evaluated at 6 and 24 hours. In addition, pretreatment with azithromycin was used to evaluate the modulatory effects on SMM-induced inflammation. SMM=supernatant from microcorpulent material from human cystic fibrosis airways. Keywords: timecourse, treatment comparisons.
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Overall design |
10 treatments total, 3-4 samples (patient codes = replicates) per treatment.
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Contributor(s) |
Ribeiro C, Hurd H, Yu Y, Braun M, Boucher R, O'Neal W |
Citation(s) |
19503797 |
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Submission date |
Feb 20, 2008 |
Last update date |
Mar 25, 2019 |
Contact name |
Wanda K. O'Neal |
E-mail(s) |
woneal@med.unc.edu
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Phone |
919-962-9866
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Organization name |
University of North Carolina at Chapel Hill
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Department |
Cystic Fibrosis/Pulmonary Research and Treatment Center
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Street address |
CB # 7248
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City |
Chapel Hill |
State/province |
NC |
ZIP/Postal code |
27599 |
Country |
USA |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (34)
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Relations |
BioProject |
PRJNA107747 |