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| Status |
Public on May 30, 2018 |
| Title |
Gene expression signatures for CD8αβ+ intraepithelial lymphocytes and CD8αβ+ splenocytes. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
CD8αβ+ intraepithelial lymphocytes (IELs) are a subset of “effector-memory-like” T cells scattered along the intestinal epithelium. To investigate if CD8αβ+ IEL can function in ways other than the conventional cytotoxic effect of CD8αβ+ T cells,CD8αβ+ IELs were compared with CD8αβ+ splenocytes (SPL) by RNA-seq.
We used microarrays to identify new functions of CD8αβ+ IELs .
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| |
|
| Overall design |
CD8αβ+ IELs and CD8αβ+ SPLs were sorted from intraepithelium of small intestines and spleens of WT mice (8–12w).
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| |
|
| Contributor(s) |
Chen B, Wei H |
| Citation(s) |
29868024 |
| |
| Submission date |
Oct 17, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Banru Chen |
| E-mail(s) |
chenbr@mail.ustc.edu.cn
|
| Organization name |
School of Life Sciences, University of Science & Technology of China
|
| Street address |
443 Huangshan Road
|
| City |
Hefei |
| ZIP/Postal code |
230027 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA414538 |
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