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Series GSE103342 Query DataSets for GSE103342
Status Public on Aug 31, 2017
Title Characterization of a clival chordoma xenograft model reveals inherent tumor genomic instability
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
Summary Patient-derived xenografts retain the genotype of the parent tumors more readily than tumor cells maintained in culture. The two reported clival chordoma xenografts are derived from recurrent tumors after radiation. In order to study the genetics of clival chordoma in the absence of prior radiation we sought to establish a patient-derived xenograft at primary resection of a clival chordoma.
 
Overall design Copy number analysis of primary tumor and 2 PDX passages using Affymetrix SNP6 arrays
 
Contributor(s) Diaz RJ, Picard D, Remke M, Rutka JT
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Submission date Aug 31, 2017
Last update date Jul 25, 2021
Contact name Marc Remke
E-mail(s) marc.remke@med.uni-duesseldorf.de
Organization name German Cancer Research Center (DKFZ)
Department Pediatric Neuro-Oncogenomics
Street address Moorenstr. 5
City Düsseldorf
State/province NRW
ZIP/Postal code 40225
Country Germany
 
Platforms (1)
GPL6801 [GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array
Samples (3)
GSM2768928 Clivial Chordoma Primary tumour
GSM2768929 Patient Derived Xenograft Serial Passage 0
GSM2768930 Patient Derived Xenograft Serial Passage 3
Relations
BioProject PRJNA401889

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE103342_Diaz_Clivial_Chordoma_Copy_Number.txt.gz 23.0 Mb (ftp)(http) TXT
GSE103342_RAW.tar 80.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record

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