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Series GSE101989 Query DataSets for GSE101989
Status Public on Jul 28, 2017
Title Deletion of 11q in neuroblastomas drives sensitivity to PARP inhibition [SEQ]
Organism Homo sapiens
Experiment type Genome variation profiling by high throughput sequencing
Summary SNP arrays were combined with next generation sequencing (NGS) to precisely define the deleted region in 17 primary 11q-loss neuroblastomas and identify allelic variants in genes relevant for neuroblastoma aetiology. We assessed PARP inhibitor olaparib in combination with other chemotherapy medications using both in vitro and in vivo models.
Overall design Next generation sequencing of genes relevant for neuroblastoma aetiology and cancer
Contributor(s) Font de Mora J, Sanmartín E
Citation(s) 28830922
Submission date Jul 28, 2017
Last update date Jul 25, 2021
Contact name Jaime Font de Mora
Organization name Instituto de Investigación Sanitaria La Fe
Lab Cellular an Molecular Bioogy Laboratory
Street address Avenida Fernando Abril Martorell, 106; Torre A, 5-07
City Valencia
ZIP/Postal code 46026
Country Spain
Platforms (1)
GPL17303 Ion Torrent Proton (Homo sapiens)
Samples (24)
GSM2720145 Neuroblastoma tumor NBX_17 (seq)
GSM2720146 Neuroblastoma tumor NBX_18 (seq)
GSM2720147 Neuroblastoma tumor NBX_19 (seq)
This SubSeries is part of SuperSeries:
GSE101990 Deletion of 11q in neuroblastomas drives sensitivity to PARP inhibition
BioProject PRJNA396156
SRA SRP113756

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Supplementary file Size Download File type/resource
GSE101989_RAW.tar 1.8 Mb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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