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| Status |
Public on Mar 28, 2013 |
| Title |
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma [tumor_genex_44k] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Single-color gene expression profiles from 649 neuroblastoma tumors were generated using 44K oligonucleotide microarrays. We aimed at determining the association of class I HOX gene expression patterns with prognostic markers in neuroblastoma.We investigated the functional consequences of HOXC9 re-expression on neuroblastoma growth and programmed cell death.
One-color gene expression analysis.
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| Overall design |
Single-color gene expression profiles from 649 neuroblastoma tumors were generated using 44K oligonucleotide microarrays. Stages were classified according to the International Neuroblastoma Staging System. The expression patterns of the 39 class I HOX genes were analyzed in 649 neuroblastoma samples by microarrays, and the association with prognostic markers was determined.
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| Contributor(s) |
Kocak H, Fischer M, Brors B, Oberthuer A |
| Citation(s) |
23579273 |
| Submission date |
Mar 27, 2013 |
| Last update date |
Apr 16, 2013 |
| Contact name |
Thomas Wolf |
| E-mail(s) |
t.wolf@dkfz.de
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| Organization name |
DKFZ
|
| Street address |
Im Neuenheimer Feld 580
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| City |
Heidelberg |
| ZIP/Postal code |
D-69120 |
| Country |
Germany |
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| Platforms (1) |
| GPL16876 |
Agilent-020382 Human Custom Microarray 44k (Feature Number version) |
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| Samples (649)
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| This SubSeries is part of SuperSeries: |
| GSE45480 |
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma |
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| Relations |
| BioProject |
PRJNA194593 |
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