Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses

Twin study identifies early immunological and metabolic dysregulation of CD8+ T cells in multiple sclerosis

Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling

LSD1 and CoREST2 Regulate STAT3 Activity to Promote Enteroendocrine Cell Differentiation in Mucinous Colorectal Cancer[scMultiome-seq]

Impact of the Multiple Sclerosis associated genetic variant CD226 Gly307Ser on human CD8 T cell functions

Polyploid cancer cells reveal signatures of chemotherapy relapse [scRNA-seq]

Single-nucleus RNA-Seq and spatial transcriptomics characterization of Alzheimer’s Disease and Down Syndrome

Unraveling the Phenotypic States of Human innate-like T Cells in thymus and blood: Insights from Single-Cell Transcriptomics

The use of ectopic volar fibroblasts to modify skin identity

Serial mRNA profiling of peripheral blood monocytes from PAH patients treated with phosphodiesterase 5 inhibitors (PDE5i) and PDE5i+macitentan

Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34+ cell therapy to induce fetal hemoglobin for sickle cell disease [scRNA]

Xenotransplanted Human Small Intestinal Organoids Reveal the Transepithelial Zinc Transport Pathway as a Key Mediator of Intestinal Adaptation in Short Bowel Syndrome

TET2 Mutant Clonal Hematopoiesis Enhances Severity of COVID-19 Related Cytokine Release Syndrome and is Associated with Increased Mortality [scMULT]

TET2 Mutant Clonal Hematopoiesis Enhances Severity of COVID-19 Related Cytokine Release Syndrome and is Associated with Increased Mortality [scRNA-seq]

Context-aware single-cell multiomics approach identifies cell-type specific lung cancer susceptibility genes

Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation [CITE-seq]

Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity

Defining the nature of human pluripotent stem cell-derived interneurons via single cell analysis

RAS-mutant AML stem cells acquire resistance to BH3 mimetics through altered BCL-2 family expression

RAS-mutant AML LSCs originate from GMPs and drive clinical resistance to BH3 mimetics [scRNA-Seq]