EZH2 mutants in isogenic cell lines

Cut&Run and MARS-seq on SU-DIPG13 cells treated Sulfopin/Vorinostat/Sulfopin+Vorinostat or DMSO

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis

EWS-FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma

Multi-omics integration identifies progenitor-state specific PBRM1-PIAS1 cooperation in repressing differentiation in epithelial tissue

Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene expression programs in bladder cancer

Dietary palmitic acid promotes a prometastatic epigenetic memory related to tumor innervation

SMYD5 is a regulator of the mild hypothermia response

Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia

Placental uptake and metabolism as determinants of pregnancy vitamin D status

Pluripotency-Independent Induction of Human Trophoblast Stem Cells from Fibroblasts

RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells

ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion

ARID1A mutations promote P300-dependent endometrial invasion through super-enhancer hyperacetylation

SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity

ARID1A-dependent maintenance of H3.3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers

BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B-cell fate decisions and accelerates development of T-cell depleted lymphomas.

Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing

Local euchromatin enrichment in lamina-associated domains anticipates their re-positioning in the adipogenic lineage