Combined mutation of C/EBPa and GATA-2 induce bi-lineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor

Combined mutation of C/EBPa and GATA-2 induce bi-lineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor [10x RNA-seq]

Sex-specific control of human heart maturation by the progesterone receptor

Combined blockade of B7-H3 and CD47 immune checkpoints is a new therapeutic strategy for β-catenin driven melanomas

Targeting TREM2 on tumor associated macrophages enhances efficacious immunotherapy

The stress response regulator HSF1 modulates natural killer cell anti-tumour immunity

Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis

A single cell atlas of human glioma under therapy

Transcriptional programs dictating Schwann cell transformation in MPNST

Osteosarcoma tumors maintain intratumoral heterogeneity, even while adapting to environmental pressures that drive clonal selection

Identification of Pathogenic Immune Cell Subsets in Checkpoint Inhibitor-induced Myocarditis

Single-cell transcriptomic atlas reveals the evolution of immune cells and molecules across multiple vertebrate species

Transcriptomics of skin reveal potential molecular mechanisms of psoriasis

The confused cell identity is associated with aggressiveness in esophageal squamous cell carcinoma

Distant antimetastatic effect of enterotropic colon cancer-derived α4β7 CD8 T cells

Down Syndrome

Comparative single-cell genomics uncovers evolutionarily conserved features and therapeutic targets in triple-negative breast cancer fibroblasts

Spatial epigenome-transcriptome co-profiling of mammalian tissues

Mesenchymal glioma stem cells trigger vasectasia, a distinct neovascularization process mediated by extracellular vesicles carrying EGFR [scRNA-seq]

Choroid plexus mast cells drive tumor-associated hydrocephalus