U4 inhibits premature cleavage and polyadenylation of pre-mRNAs [mRNA 3'-seq]

U4 inhibits premature cleavage and polyadenylation of pre-mRNAs

The Transcriptional Cofactor SKI Regulates Medullary Thymic Epithelial Cell Differentiation and Peripheral T Cell Responses

Remodeling of anti-tumor immunity with antibodies targeting a p53 mutant

A glial circadian gene expression atlas reveals cell type and disease-specific reprogramming in response to amyloid pathology or aging

PI3Kg in B cells promotes antibody responses and generation of antibody-secreting cells [scRNA-seq]

CCR1 drives immunosuppressive properties of tumor associated macrophages in pancreatic cancer

Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth [scRNA-seq]

Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm [scRNA-seq]

Unraveling the Role of Srsf1 in Brown Adipose Tissue Thermogenic Function through Single-Nucleus RNA Sequencing.

Iron chelation therapy elicits innate immune control of metastatic ovarian cancer

RIG-I sensing of self-RNA in aged endothelial cells links cellular senescence with an interferon gene signature I

RIG-I sensing of self-RNA in aged endothelial cells links cellular senescence with an interferon gene signature

Single-cell transcriptional analysis of kidney from aging mice with podocyte specific RARRES1 overexpression

Cellular fitness of MYC-driven cancer cells to genetic and pharmacologic perturbations in normoxia, hypoxia and 3D

Transcriptome analysis to investigate the role of ACLY pathway in senescent cells.

Loss of Inpp5d has disease-relevant and sex-specific effects on glial transcriptomes

Enhancer-AAVs allow genetic access to diverse populations of astrocytes and oligodendrocytes across species

Fecal microbiota transfer from autoimmune dry eye disease model mice to conventional mice induces ocular surface inflammation and stereotypic B cell receptor repertoire development in lacrimal gland

CMS121 partially attenuates disease progression in mouse models of Huntington's disease