Spontaneous DIPG Modeling Reveals Novel H3.3 K27M-Mediated Oncogenic Mechanisms Acting Through Epigenetic Effects [RNA-seq]

H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo [RNA-Seq]

Identification of 17-DMAG as a novel KDM4B inhibitor for combination therapy [RNA-seq]

Identification of 17-DMAG as a novel KDM4B inhibitor for combination therapy

Quantitative assessment of transcriptomic differences between ASPcKO and ASPcKOP7cKO flow cytometry-sorted murine FN-RMSs by RNA sequencing

Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity

Exceptional response of high-risk neuroblastoma to RBM39 degrader Indisulam (RNA-Seq)

Exceptional response of high-risk neuroblastoma to RBM39 degrader Indisulam

Targeting KDM4B to disrupt the core regulatory transcription network governed by PAX3-FOXO1 in high-risk rhabdomyosarcoma

Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma [RNA-Seq]

Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma [RNAseq_LHCN_hg19]

Genome-wide mapping of oncogenic pathways and genetic modifiers of chemotherapy using a high-risk hepatoblastoma genetic model

PAX3-FOXO1 expression in endothelial progenitors dictates myogenic reprogramming and rhabdomyosarcoma identity

PAX3-FOXO1 drives tumor formation from multiple lineages [RNA-seq]

Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma

KDM4 histone lysine demethylases maintain the adrenergic core regulatory circuitry programed by MYCN in neuroblastoma

KDM4 inhibition disrupts the core regulatory transcriptional circuitry in MYCN-driven neuroblastoma [RNA-seq]

RNA-seq of KDM4A, B and C siRNA knockdown in NB cells

A genetic mouse model of malignant peripheral nerve sheath tumor with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human tumors