How Mycobacterium tuberculosis builds a home: Single-cell analysis reveals M. tuberculosis ESX-1-mediated accumulation of anti-inflammatory macrophages in infected mouse lungs

Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

Tabula Muris

Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation

Single-cell and spatial profiling identify three response trajectories to pembrolizumab and radiation therapy in triple negative breast cancer

Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs novel combination cancer therapy strategies [mouse]

A Panoramic View of Cell Population Dynamics in Mammalian Aging

Partial pluripotent reprogramming in C2C12 myoblasts

Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas [scRNA-seq]

Intratumoral antigen-signalling traps CD8+ T cells to confine exhaustion to the tumour site (scRNA-Seq)

Time-Course Analysis of Hepatic Single-Nuclei RNA-Sequencing in Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)

Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

Correction of age-associated defects in dendritic cell functions enables CD4+T cells to eradicate tumors in the elderly

Hemorrhage-induced NRF2 signaling in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance

Age-related epithelial defects limit thymic function and regeneration [single cell]

Arthritogenic SKG T cells have a transcriptional program of activation and a repertoire pruned by superantigen

A contamination focused approach for optimizing the single-cell RNA-seq experiment

Lineage-specific intolerance to oncogenic drivers restricts histological transformation [scRNA-Seq]