Mechanotransduction mediated by cyclical respiratory motion maintains lung alveolar epithelial cell fate

10X Single cell RNAseq (scRNAseq) analysis of intestinal epithelial cells (IECs) from murine small intestinal organoids treated with vehicle (DMSO) or LXR agonist GW3965.

10X Visium Spatial transcriptomics of murine colon at d14 (mucosa healing) in B cell sufficient/deficient mice

10X Visium Spatial transcriptomics of murine colon in steady state and during recovery after DSS colitis

10X single-cell RNA-seq profiling of ccRCC model tumors and normal kidney tissue

10X single-cell RNASeq profiling of immune infiltrate from mutant IDH1 ICC tumors treated with AG120 (mIDH1 inhibitor) or vehicle

A Cellular Atlas of the Down Syndrome Brain Identifies Accelerated Oligodendrocyte Precursor Cell Senescence

A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

A Growth Factor-Expressing Macrophage subpopulation orchestrates regenerative inflammation via GDF-15

A Growth Factor-Expressing Macrophage subpopulation orchestrates regenerative inflammation via GDF-15 [scRNA-seq]

A Humanized Monoclonal Antibody Targeting an Ectonucleotidase Rescues Heart Function after Myocardial Infarction

A Single Trophoblast Layer Acts as the Gatekeeper at the Endothelial-Hematopoietic Crossroad in the Placenta

A blood-brain barrier transport vehicle improves brain biodistribution of a TREM2 antibody and enhances microglial metabolism via receptor clustering

A body-brain circuit regulating body inflammatory responses

A centrosomal defect of intestinal stem cells predisposes to Crohn’s Disease

A centrosomal defect of intestinal stem cells predisposes to Crohn’s Disease [scRNA-Seq]

A combination treatment based on drug repurposing demonstrates mutation agnostic efficacy in pre-clinical retinopathy models.

A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models [scRNA-seq: Rd10]

A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models [scRNA-seq: Rpe65-KO]

A developing HPA axis permits neonatal immune sensitivity to common allergens [scRNA-Seq]