A primed immune transcriptional program is activated in oligodendroglia in multiple sclerosis

SMYD5 is a regulator of the mild hypothermia response

Aberrant translation regulation by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives HNSCC progression

Extracellular niche and tumor microenvironment enhance the impact of KRAS inhibitors in pancreatic cancer models.

A neutropenia-associated transcription factor mutation differentially impacts target genes in the cell-states traversed during granulocyte specification and commitment

HOTTIP reinforces CTCF-defined TAD boundaries by forming R-loops to drive Wnt/b-catenin target gene expression in AML leukemogenesis

Zika virus co-opts miRNA networks to persist in placental microenvironments detected by spatial transcriptomics

Programmable transcript-specific enrichment for single-cell sequencing enables profiling of rare cell states

Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis

Mouse kidneys with ischemia-reperfusion injury; Human kidneys with acute kidney injury; RELA binding sites in primary human proximal tubular cells

A genetic-metabolic axis for metastatic liver organotropism

Decoder-seq enhances mRNA capture efficiency in spatial RNA sequencing

Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics

Droplet Hi-C for fast and scalable profiling of chromatin architecture in single cells