Identifying non-genetic determinants of malignant clonal fitness at single cell resolution

Aberrant homeodomain-DNA cooperative dimerization underlies distinct developmental defects in two dominant CRX retinopathy models

Sequence determinants of human gene regulatory elements

Systematic Analysis of Transcription Factors Binding to Noncoding Variants

Enhancer grammar of liver cell types and hepatocyte zonation states

The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery

Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation.

Combinatorial quantification of 5mC and 5hmC at individual CpG dyads and the transcriptome in single cells reveals modulators of DNA methylation maintenance fidelity 

Enhanced detection of RNA modifications with high-accuracy nanopore RNA basecalling models

Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants

CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing

PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse [GeoMx]

Inherited functional regulatory risk variants for common human cancers [MPRA]

TRACE-Seq Reveals Clonal Reconstitution Dynamics of Gene Targeted Human Hematopoietic Stem Cells

Simultaneous measurement of DNA repair activities and mRNA abundance in single cells

Seq-Scope: Submicrometer-resolution spatial barcoding technology that enables microscopic examination of tissue transcriptome at single cell and subcellular levels

Dual Chromatin Repressors Regulate Hippocampal Development

Mapping of clonal lineages across developmental stages in human neural differentiation

De novo enhancer function in divergent hominin haplotypes

Integrated multi-omics analysis of zinc finger proteins uncovers roles in RNA regulation.