The tRNA methyltransferase Mettl1 governs ketogenesis through translational regulation and drives metabolic reprogramming in cardiomyocyte maturation

Promotion of TLR7-MyD88-dependent Inflammation and Autoimmunity through Stem-loop Changes in Lnc-Atg16l1

ITPK1 sensitizes tumor cells to IgA-dependent neutrophil killing in vivo [CRISPR Epistasis]

ITPK1 sensitizes tumor cells to IgA-dependent neutrophil killing in vivo [CRISPR focused]

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER [CRISPR]

Encoding of odors by mammalian olfactory receptors

Ileal Crohn’s disease exhibits reduced activity of phospholipase C-β3 (PLC-β3)-dependent Wnt/b-catenin signaling pathway

Young and Aged Striatal Astrocyte MERFISH Panel

Novel integrated multiomics analysis reveals Itgbl1-mediated regulation of fibrogenesis through antagonism of Tgfβ1 and IL1β signaling.

Enhanced Spatial Transcriptomics Analysis of Mouse Lung Tissues Revealed Cell-Specific Gene Expression Changes Associated with Pulmonary Hypertension

scRNA-seq, snATAC-seq, and spatial transcriptomics analysis of mammary glands of aged female mice

Ago2 protects against diabetic cardiomyopathy via activating mitochondrial gene translation [Ribo-seq]

3D genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes

Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance. [Ribo-seq]

Alarmin-loaded extracellular lipid droplets induce airway neutrophil infiltration during type 2 inflammation

Non-Canonical PRC1.1 is required for the activity of Menin-MLL1 Inhibitors in NUP98-Rearranged AML [CRISPR-Seq]

Non-Canonical PRC1.1 is required for the activity of Menin-MLL1 Inhibitors in NUP98-Rearranged AML [PRO-Seq]

A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance [DNA-seq]

Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade

FUS-mediated inhibition of myogenesis by suppressing TNNT1 production [RIP-seq]