Enhanced detection of RNA modifications with high-accuracy nanopore RNA basecalling models

Position-dependent function of human sequence-specific transcription factors

Time-resolved RNA sequencing reveals distinct post-transcriptional regimes during zebrafish embryogenesis

Measuring stress response upon tissue dissociation using SLAMseq in bulk and single cells

Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler

A single-cell massively parallel reporter assay detects cell type specific cis-regulatory activity

Joint epigenome profiling reveals cell-type-specific gene regulatory programs in human cortical organoids

Experimental tests strongly challenge the evidence of a healthy human blood microbiome

DNA replication-timing boundaries separate stable chromosome domains with cell-type-specific functions

Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

3′ sequencing from human Huntington's disease and control motor cortex and cerebellum.

YY1 is a structural regulator of enhancer-promoter loops

Simultaneous quantifications of protein-DNA contacts and transcriptomics in single cells

XPO5 is required for miRNA biogenesis and promotes primary miRNA processing independent of RanGTP

Single-Cell Genotyping of Transcriptomes

Single-cell multi-omic profiling of chromatin conformation and DNA methylome

Saturation mutagenesis of disease-associated regulatory elements

The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1

Rett Syndrome linked to defects in forming the MeCP2/Rbfox/LASR complex in mouse models