NFI transcription factors regulate zonal olfactory receptor expression

Single cell- Cluster-RNA seq and Spatial Transcriptomics from the trunk of mouse embryos of different genotypes (wild type, Pax2-GFP, Pax2-GFP; Gata3 knockout) and developmental stages (E8.75, E9.5, E11.5) [Spatial Transcriptomics]

Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection.

Perturb-map coupled with spatial transcriptomics identifies mutation associated gene signatures in a mouse model of lung adenocarcinoma

Excitatory SST neurons in the medial paralemniscal nucleus control repetitive self-grooming and encode reward

Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs novel combination cancer therapy strategies

INPP5D limits plaque formation and glial reactivity in the APP/PS1 mouse model of Alzheimer’s disease

APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge

IL-1b+ tumor-associated macrophages fuel pathogenic inflammation in pancreatic cancer

Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex

Molecular reframing of fibroblasts during resolution of arthritis

MacroH2A restricts melanoma progression via inhibition of chemokine expression in cancer-associated fibroblasts [spatial transcriptomics]

Single cell and spatial transcriptomics analysis of kidney double negative T lymphocytes in normal and ischemic mouse kidneys [spatial transcriptomics]

Single cell and spatial transcriptomics analysis of kidney double negative T lymphocytes in normal and ischemic mouse kidneys

Pharmacological targeting Netrin-1 inhibits EMT in cancer [Visium]

Pharmacological targeting Netrin-1 inhibits EMT in cancer

Helicase-like transcription factor (HLTF)-deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in intravascular metastatic niches [Spatial]

Helicase-like transcription factor (HLTF)-deleted CDX/TME model of colorectal cancer increased transcription of oxidative phosphorylation genes and diverted glycolysis to boost S-glutathionylation in intravascular metastatic niches

Aging- and Alcohol-Associated Spatial Transcriptomic Signature in Mouse Acute Pancreatitis

In vivo single-cell CRISPR uncovers distinct TNF-α programs in tumor evolution