Measuring stress response upon tissue dissociation using SLAMseq in bulk and single cells

A single-cell massively parallel reporter assay detects cell type specific cis-regulatory activity

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

PRMT5 Promotes Progression of Chronic Lymphocytic Leukemia

TCR-Vγδ usage distinguishes pro- and anti-tumor intestinal γδ T cell subsets

Metabolic Programs of T Cell Tissue Residency Empower Tumor Immunity

Multiomic analysis reveals conservation of cancer associated fibroblast phenotypes across species and tissue of origin

T cells specific for alpha-myosin drive immunotherapy related myocarditis

ETV6 Represses Inflammatory Response Genes and Regulates HSPC Function During Stress Hematopoiesis in Mice

Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements

The Triptryium wilfordii derivative celastrol has anti-fibrotic effects in systemic sclerosis

heart healthy and heart diseased SCGs

Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens

A Lactate-induced SREBF2-dependent genetic program drives an immunotolerant dendritic cell population during cancer progression

Global organization of the B cell genome by the transcription factor Pax5 [Hi-C]

Global organization of the B cell genome by the transcription factor Pax5

In situ Hi-C profiles of mouse CD4+ T cells, CD8+ T cells and B cells

Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

Hi-C profiling of B-cell progenitors from Erg KO and WT mice

Dissection of the 4D chromatin structure of the alpha-globin locus through in vivo erythroid differentiation with extreme spatial and temporal resolution [CITE-seq]