In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation [Capture-C]

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation

Nuclear Organization of Lens Epithelium and Fiber Cells in Newborn Lens

Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution

Enhancer remodeling overcomes therapeutic resistance driven by epigenetic evolution in cancer [HiChIP]

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration [Hi-C]

Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration

Epigenetic evolution of the Ly49 gene family

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology.

The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain

A distal super enhancer mediates estrogen-dependent mouse uterine–specific gene transcription of Insulin-like growth factor 1 (Igf1)

Dynamic promoter-enhancer contacts contribute to spatiotemporal gene expression during mouse fetal development

Enhancer-dependence of gene expression increases with developmental age

Hi-C sequencing data of WT and Zeb2 enhancer mutant splenic CD8+ T cells

G9a plays distinct roles in maintaining DNA methylation, retrotransposon silencing and chromatin looping

The energetics and physiological impact of cohesin extrusion

WAPL functions as a rheostat of Protocadherin isoform diversity that controls neural wiring

Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression

FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression [HiChIP]