A primed immune transcriptional program is activated in oligodendroglia in multiple sclerosis

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

The Triptryium wilfordii derivative celastrol has anti-fibrotic effects in systemic sclerosis

Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of The Pancreas Identifies NKX6-2 Expression as a Driver of Gastric Differentiation and Indolent Biological Potential

In situ Hi-C in Smchd1 wild-type and Smchd1 deleted neural stem cells.

Smchd1 in neural stem cells.

In situ Hi-C in Smchd1 wild-type and Smchd1 deleted neural stem cells. [II]

Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

The transcriptional and architectural resetting of stem cell identity during G1 entry

Emergence of a high-plasticity cell state during lung cancer evolution

T cell receptor is required for differentiation but not maintenance of intestinal CD4+ intraepithelial lymphocytes

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes

The thymoproteasome hardwires the TCR repertoire of CD8+ T cells in the cortex independent of negative selection

Multi-Dimensional Profiling Reveals a Molecularly Distinct Injury-Responsive Population of Regulatory T Cells

An NPAS4:NuA4 complex couples synaptic activity to DNA repair

Integrated spatial multi-omics reveals fibroblast fate during tissue repair

WAPL functions as a rheostat of Protocadherin isoform diversity that controls neural wiring

Integration of whole transcriptome spatial profiling with protein markers

An Epigenetic Memory of Inflammation Induces Context-Dependent Lineage Plasticity in the Pancreas with Divergent Phenotypic Outcomes