Cardiac Applications of CRISPR/AAV-Mediated Precise Genome Editing

Characterization of maturational enhancer activity by massively parallel reporter assay [amplicon-Seq]

Identification of Hedgehog signaling responsive genes in A. sagrei and M. musculus via transcriptional profiling

A single-cell massively parallel reporter assay detects cell type specific cis-regulatory activity

Sequencing of metabolically labeled transcripts in single cells from RPE1-FUCCI cells and murine intestinal organoids.

MAFG-driven astrocytes promote CNS inflammation

Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Hierarchical chromatin regulation during blood formation uncovered by single-cell sortChIC

A primed immune transcriptional program is activated in oligodendroglia in multiple sclerosis

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

Charged tRNA profiling of mcf10a, HCC1806 cells, polysome profiling, RNA-Seq and Ribo-Seq in 4T07 cells upon LARS knockdown by shRNA, and RNA-Seq of ribosome-associated RNAs in Lars depleted PyMT tumors 

PRMT5 Promotes Progression of Chronic Lymphocytic Leukemia

Mutant-SETBP1 activates transcription of Myc programs to accelerate CSF3R-driven myeloproliferative neoplasms

Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes

RNA stability controlled by m6A methylation provides X to autosome compensation in mammals

TCR-Vγδ usage distinguishes pro- and anti-tumor intestinal γδ T cell subsets

A myeloid maturation program initiated by nucleotide depletion during S phase [CRISPRi screen]

The Triptryium wilfordii derivative celastrol has anti-fibrotic effects in systemic sclerosis

Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens

Cdx and T Brachyury co-activate growth signaling in the embryonic axial progenitor niche.