Chromatin structure and CTCF across the MCF10 breast cancer progression series (HiC)

Exonuclease combinations reduce noises in 3D genomics technologies

hictk: blazing fast toolkit to work with .hic and .cool files

HiCrayon reveals distinct layers of multi-state 3D chromatin organization

Three-dimensional genome architecture persists in a 52,000-year-old woolly mammoth skin sample

Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci

Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci

A three-dimensional map of the human genome at kilobase resolution reveals prinicples of chromatin looping

Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing

Distinct Enhancer Classes in Drosophila Bind Different Architectural Proteins and Mediate Unique Chromatin Interactions and 3D Architecture [Hi-C]

HiChIP: Efficient and sensitive analysis of protein-directed genome architecture

Myc regulates chromatin decompaction and nuclear architecture during B cell activation

Sub-kilobase resolution Kc167 cell Hi-C

Evolutionary Principles Predict 3D Chromatin Organization

Hi-C from A549 (ENCSR244BBG)

Hi-C from A549 (ENCSR393LOP)

Hi-C from A549 (ENCSR499RVD)

Hi-C from A549 (ENCSR662QKG)

Hi-C from A549 (ENCSR757IVO)

Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation