Therapeutic Delivery of CCL2 Modulates Immune Response and Restores Host-microbe Homeostasis

Preventive Treatment with a CD73 Small Molecule Inhibitor Enhances Immune Surveillance in K-Ras Mutant Pancreatic Intraepithelial Neoplasia

Helminth protein enhances wound healing by inhibiting fibrosis and promoting tissue regeneration

Lgr5 Marks Stem/Progenitor Cells Contributing to Epithelial and Muscle Development in the Mouse Esophagus

Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis

Personalized dendritic cell vaccine facilitates the preparation of neoantigen-reactive T cells for adoptive transfer (scTCR-Seq)

Multi-omics Analysis Revealing the Impact of Excessive Maternal Folate Supplementation on Offspring Brain Development [spatial transcriptome]

scRNA-Seq reveals anti-fibrotic mechanisms of TRPC6 inhibition [Spatial Transcriptomics]

Translation efficiency in the mouse liver upon 24h chow or ketogenic diet fed

Spatial and scRNAseq profiling of murine glioblastomas treated with and without anti-CSF-1R inhibitors

Primary nasal viral infection rewires the tissue-scale memory response

Intratumoral antigen-signalling traps CD8+ T cells to confine exhaustion to the tumour site (scRNA-Seq)

Infection history imprints prolonged changes to the Kupffer cell epigenome, transcriptome and function of Kupffer cells

Precise in-vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA

Dynamic Chromatin Boundaries of TCR Loci Coincide V(D)J recombination During T Cell Development

Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity

Spatial analysis of murine lungs exposed to fibrogenic stress

Treg insufficiency in autoimmune diabetes is driven by selective loss of Neuropilin-1 on intra-islet regulatory T cells

LAG3 and PD1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN gamma-dependent anti-tumor immunity

Programmable transcript-specific enrichment for single-cell sequencing enables profiling of rare cell states