A conserved noncoding locus modulates random monoallelic Xist expression across a TAD boundary

MAFG-driven astrocytes promote CNS inflammation

H4K20me3 methyltransferase SUV420H2 shapes the three-dimensional chromatin landscape of pluripotent embryonic stem cells

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

Dichotomous Engagement of HDAC3 Activity Governs Inflammatory Responses

Hi-C sequencing analysis of wild-type, β-actin knockout and β-actin hetereozygous mouse embryonic fibroblasts

Role of beta-actin in mouse embryonic fibroblasts (MEFs)

RNA promotes the formation of spatial compartments in the nucleus

H1 linker histones regulate the balance of repressive and active chromatin domains via localized genomic compaction [Hi-C]

Calcium Signaling Prompts NIPBL Recruitment at Active Enhancers and Promoters via Distinct Mechanisms to Reconstruct Genome Compartmentalization

The role of Phc1 in organizing the chromatin interactions of the Nanog locus in ESCs

Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler

CRISPR and biochemical screens identify MAZ as a co-factor in CTCF-mediated insulation at Hox clusters

Fat1 deletion promotes hybrid EMT state with enhanced tumor progression, stemness, and metastasis

Oct1 cooperates with Smad transcription factors to promote mesodermal lineage specification

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology.

Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential.

The Pol II prenitiation complex (PIC) influences Mediator binding but not promoter-enhancer looping

Xist-seeded nucleation sites form local concentration gradients of silencing proteins to inactivate the X-chromosome

Transcriptional changes to cytotoxic stresses are driven by HSF-activated genes and enhancers [PRO-seq]