In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation

Negative Elongation Factor (NELF) regulation of muscle progenitor expansion assessed via Precision Run-On Sequencing (PRO-seq)

9sCa: MSL2 is an allelic dosage sensor in mammals

Reduced RXRa signaling increases dry eye disease inducing gdT17 cells in the conjunctiva

Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination

Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding

The transcriptional and architectural resetting of stem cell identity during G1 entry

Mitotic bookmarking by H3K27 acetylation is critical for rapid transcriptional, but not architectural, resetting of stem cell-related genes and enhancers upon G1 entry [PRO-seq]

Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene

Transcription Pausing Regulates Mouse Embryonic Stem Cell Differentiation [GRO-seq]

Transcription Pausing Regulates Mouse Embryonic Stem Cell Differentiation

ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress [EdU-seq]

ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress

Histone variant H3.3 facilitates open chromatin at promoters [GRO-seq]

Histone variant H3.3 facilitates open chromatin at promoters.

3D genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes [ChIRP_seq]

3D genome organization during TGFB-induced transcription requires nuclear microRNA and G-quadruplexes

NEUROD1 is critical for the initial cell identity determination and differentiation of the endocrine progenitors in the pancreas.

Sequencing short capped RNAs captures acute transcription initiation and identifies promoter and distal regulatory elements across eukaryotes from total RNA

ATRX histone binding and helicase activities have distinct roles in neuronal differentiation