Long range regulation of transcription scales with genomic distance in a gene specific manner

CRISPR-SaCas9-KKH targeting of miR-21 through a single adeno-associated virus vector prolongs survival of GB-bearing mice

Gut-Lung Microbiota Dynamics in Mice Exposed to Nanoplastics

ITPK1 sensitizes tumor cells to IgA-dependent neutrophil killing in vivo [CRISPR Epistasis]

ITPK1 sensitizes tumor cells to IgA-dependent neutrophil killing in vivo

Expansion of in vivo HDAd-transduced HSPCs by constitutive expression of tHMGA2 without additional treatment allows for therapeutically relevant transgene expression in HSPC progeny cells without clonal dominance.

Characterization and bioinformatic filtering of ambient gRNAs in single-cell CRISPR screens using CLEANSER [CRISPR]

Saturation genome Editing of BRCA2 variants from C-terminal DNA binding domain

Identification of rejection-associated indirect CD4 T cell epitopes provides a target for donor-specific transplant tolerance

Mouse enteric neurons control intestinal plasmacytoid dendritic cell function via serotonin-HTR7 signaling [16S]

Mouse enteric neurons control intestinal plasmacytoid dendritic cell function via serotonin-HTR7 signaling

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene [Tagmentation]

The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming

Targeted Amplicon Sequencing: The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming

Chromatin Conformation Dynamics are essential to Control the Transcription of INK4/ARF locus

Chromatin conformation capture (4C-seq) from mouse liver

In vivo CRISPR base editing for treatment of Huntington’s disease

guidedNOMe-seq quantifies chromatin states at single allele resolution for hundreds of custom regions in parallel [guidedNOMe-seq]

SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire