3D structures of individual mammalian genomes reveal principles of nuclear organization

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

miRNA-target chimeras identified with CLEAR-CLIP reveal miRNA 3' end pairing as a major determinant of Argonaute binding in vivo [mouse cortex CLEAR-CLIP]

Determination of direct binding targets of Quaking RNA binding proteins

Megadomains and superloops form dynamically during X-chromosome inactivation but are dispensable for silencing and escape

Genetic models reveal cis and trans immune-regulatory activities for lincRNA-Cox2 in vivo (macrophages)

Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination

Epigenetic Enhancer Marks and Transcription Factor Binding Influence Vk Gene Rearrangement in Pre-B Cells and Pro-B Cells [VDJ-seq]

CtIP is essential for early B cell proliferation and development in mice

Phosphorylation at the S2056 1 cluster of DNA-PKcs is dispensable for lymphocyte development and class switch recombination in mice.

Indel rate analysis:Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy

DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination

CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining

T cell receptor is required for differentiation but not maintenance of intestinal CD4+ intraepithelial lymphocytes

Dnmt1 has global de novo methylation activity and is specifically targeted to transposable elements

FATC domain deletion compromises ATM protein stability, lymphocyte development, and promotes lymphomagenesis

16S sequencing of mouse gut microbial DNA after 10 days of intermittent fasting or ad libitum with and without vancomycin treatment

Neuronal Nsun2 deficiency is associated with codon-specific epitranscriptomic dysregulation of Gly-tRNAs and corresponding proteomic shift impacting synaptic signaling and behavior

RNA Sequencing Analysis of T Cell Receptor Alpha and Beta Chain in Thymic WT versus CIC-deficient CD4+ SP Non-Treg and Treg Cells.

Neurons burdened by DNA double strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration.