Bisulfite-free base-resolution sequencing of oxidized cytosines (APOBEC-seq) reveals a ubiquitous role of thymine DNA glycosylase in active gene promoters and an interaction with MBD3/NuRD

Synthetic essentiality of thymine DNA glycosylase in p53-deficient cancer

Chromatin-associated LTR RNA m5C oxidation by TET2 regulates leukemogenesis

Tox reinforces the phenotype and longevity of exhausted T-cells in chronic viral infection

p300 suppresses the transition of myelodysplastic syndrome to acute myeloid leukemia

Insights into the regulation of the brain-placental axis

DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells

Mouse totipotent stem cells captured and maintained through spliceosomal repression

Transcriptional reprogramming of skeletal muscle stem cells by the niche environment

Hypoxia induces an early primitive streak signature, enhancing spontaneous elongation and lineage representation in gastruloids

Unveiling E2F4, TEAD1 and AP-1 as regulatory transcription factors of the replicative senescence program by multi-omics analysis

Induction of mouse totipotent stem cells by a defined chemical cocktail

Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet

YTHDF2 inhibition potentiates radiotherapy by reprogramming suppressive myeloid cells

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

Global m6A-modified mRNAs in the uterus of wild-type mouse

B16 and 4T1 cell lines with decitabine treatment

Dual gene activating and repressive functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation

Brain methylome remodeling sustains neuronal activity gene expression in mice exposed to maternal immune activation [5mC]

Brain methylome remodeling sustains neuronal activity gene expression in mice exposed to maternal immune activation [5hmc]