The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells

Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease

HOXBLINC is aberrantly expressed in acute myeloid leukemia and functions as a potent oncogenic long non-coding RNA in leukemogenesis

Replicational dilution of H3K27me3 in mammalian cells and the role of poised promoters

MAFG-driven astrocytes promote CNS inflammation

Nutrient regulation of the islet epigenome controls adaptive insulin secretion

Genome-wide chromatin analyses and RNA-seq of liver cells upon YAP induction

Integrative single-cell chromatin and transcriptome profiling uncovers cell-type specific regulatory interactions

Temporal evolution of cellular heterogeneity during the progression to advanced, AR-negative prostate cancer

m6A directs the demethylation of histone H3K9me2 co-transcriptionall

Transcriptome profile of ENDOC-BH1 cells and isolated murine islets modulating TFEB expression

Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs).

A single-cell epigenetic atlas of human IDH-mutant glioma

Single-cell joint detection of chromatin occupancy and transcriptome enables higher-dimensional epigenomic reconstructions

Fat1 deletion promotes hybrid EMT state with enhanced tumor progression, stemness, and metastasis

Disruption of higher order nuclear condensates by a dominant negative FOXN1 mutation causes immunodeficiency

BAP1 activity regulates Polycomb occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition

HOTTIP reinforces CTCF-defined TAD boundaries by forming R-loops to drive Wnt/b-catenin target gene expression in AML leukemogenesis

KLF5 governs sphingolipid metabolism and barrier function of the skin