The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis

Replicational dilution of H3K27me3 in mammalian cells and the role of poised promoters

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

A single-cell epigenetic atlas of human IDH-mutant glioma

HOTTIP reinforces CTCF-defined TAD boundaries by forming R-loops to drive Wnt/b-catenin target gene expression in AML leukemogenesis

ZNF384 fusion oncoproteins drive lineage aberrancy in acute leukemia

Scavenger Receptor SCARB2 Drives Hepatic Carcinoma Initiation by Enhancing MYC Transcriptional Activity and Supporting Cancer Stem Cell Traits.

Hepatocytes demarcated by EphB2 contribute to the progression of non-alcoholic steatohepatitis

TEAD1 trapping by the Q353R-Lamin A/C causes dilated cardiomyopathy.

The transcriptional and regulatory identity of erythropoietin producing cells

An engineered Sox17 induces somatic to neural stem cell fate transition independently from pluripotency reprogramming

An activity-specificity trade-off encoded in human transcription factors

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

TRIM28 modulates progesterone and estrogen signaling in endometrium

ETV6 Represses Inflammatory Response Genes and Regulates HSPC Function During Stress Hematopoiesis in Mice

Dissecting developmental disorders caused by CTCF mutation at R567

Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B-cell fate decisions and accelerates development of T-cell depleted lymphomas.

Comparative single cell epigenomic analysis of gene regulatory programs in the rodent and primate motor cortex

Chemically induced revitalization of damaged hepatocytes for regenerative liver repair