Topoisomerase 1 Nicking-dependent HP1gamma Engagement Mediates Acute Activation of Phase-separated Enhancers

Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs).

Krab-ZFPs Inhibit Retrovirus by Targeting PBS Sites

Chromatin architecture of B cell development during the humoral immune response

Epigenetic basis of oncogenic-Kras mediated epithelial-cellular proliferation and plasticity

The SWI/SNF subunit Dpf2 licenses Nrf2-dependent gene expression to enforce multilineage control of inflammation

EVI1 drives leukemogenesis through aberrant activation of ERG

TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs

BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state

BORIS/CTCFL epigenetically reprograms clustered CTCF binding sites into alternative transcriptional start sites.

KDM8 epigenetically controls cardiac metabolism to prevent initiation of dilated cardiomyopathy

Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B-cell fate decisions and accelerates development of T-cell depleted lymphomas.

Engrailed-1 Promotes Pancreatic Cancer Metastasis

Chemically induced revitalization of damaged hepatocytes for regenerative liver repair

THAP1 is a master regulator of zinc finger transcription factors guiding gastrulation of murine embryos

Chromatin-associated LTR RNA m5C oxidation by TET2 regulates leukemogenesis

Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution

Hammer-seq to measure kinetics of DNA methylation maintenance in HeLa cells

Epigenetic dysregulation from chromosomal transit in micronuclei